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Diagnostic accuracy of hematoxylin-eosin staining in comparison to calretinin and S100 for the assessment of ganglion cells in rectal biopsy

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Title: Diagnostic accuracy of hematoxylin-eosin staining in comparison to calretinin and S100 for the assessment of ganglion cells in rectal biopsy

Authors: Zainab Waleed Aziz Aziz, Bassam Khalid Al Hajjar, Ziyad Ahmed Abed Al Hajjar, Ehsan Mahmood Abdullah Almola, Nazar Mohammed Taher Jawher, Radhwan Khudhur Muhammad Muhammad

Journal: Journal of Pakistan Medical Association

HEC Recognition History
Category From To
Y 2024-10-01 2025-12-31
X 2023-07-01 2024-09-30
X 2022-07-01 2023-06-30
X 2021-07-01 2022-06-30
X 2020-07-01 2021-06-30
W 2012-07-01 2020-06-30
X 2011-05-13 2012-06-30
Y 1900-01-01 2005-06-30

Publisher: Pakistan Medical Association.

Country: Pakistan

Year: 2022

Volume: 72

Issue: 6

Language: en

DOI: 10.47391/JPMA.3368

Categories
Pediatric Pathology (10) Immunohistochemistry (190) Histopathology (437) Pathology (12652) Gastroenterology (8625)

Abstract

Objectives: To assess the diagnostic accuracy of haematoxylin-eosin staining in clinically suspected Hirschsprung disease, and to compare the findings with calretinin and S100 immunohistochemistry.
Method: The retrospective study was conducted at the AL-Khansaa Teaching Hospital, Nineveh, Iraq, and comprised data from January 2017 to October 2020 of rectal suction biopsies of patients with clinically and radiologically suspected Hirschsprung disease. Histopathology and immunohistochemistry were performed. Data was analysed using SPSS 16.
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