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Mammary analogue secretory carcinoma of the parotid gland—a rare tumour entity

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Title: Mammary analogue secretory carcinoma of the parotid gland—a rare tumour entity

Authors: Syeda Tehmina Junaid, Soima Ali Muhammad, Zeba Ahmed, Khubeb, Rajesh Kumar Vasandani, Jawad Ahmed

Journal: Journal of Pakistan Medical Association

HEC Recognition History
Category From To
Y 2024-10-01 2025-12-31
X 2023-07-01 2024-09-30
X 2022-07-01 2023-06-30
X 2021-07-01 2022-06-30
X 2020-07-01 2021-06-30
W 2012-07-01 2020-06-30
X 2011-05-13 2012-06-30
Y 1900-01-01 2005-06-30

Publisher: Pakistan Medical Association.

Country: Pakistan

Year: 2022

Volume: 72

Issue: 2

Language: en

DOI: 10.47391/JPMA.5472

Categories
Salivary Gland Tumors (6) Rare Tumors (2) Head and Neck Surgery (333) Pathology (12652) Oncology (10297)

Abstract

Mammary analogue secretory carcinoma (MASC) is a salivary gland tumour with low-grade potential and specific FTV6 derangement having translocation of chromosomes t (12;15) (p13;q25). It shares a similar morphological as well as an immunohistochemical profile with secretory carcinoma (SC) of the breast making it a diagnostic enigma.
In this report, we discuss the case of a 65-year-old male patient, who presented with a complaint of right-sided facial swelling. To rule out the differential, he underwent various diagnostic modalities, including magnetic resonance imaging, fine-needle aspiration and it’s the tumour’s microscopic and immunohistochemical properties were also reviewed. Parotidectomy along with concurrent chemo-radiotherapy was performed to eradicate the growing mass.
Keywords: Mammary analogue secretory carcinoma, immunohistochemical, Parotidectomy.

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