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Title: Frequency of French-American-British subtypes of acute myeloid leukaemia in a tertiary care hospital of Karachi
Authors: Irtiza Ahmed Bhatti, Ghulam Haider, Youksal Intikhab Khan, Taher Saifuddin
Journal: Journal of Pakistan Medical Association
Publisher: Pakistan Medical Association.
Country: Pakistan
Year: 2022
Volume: 72
Issue: 3
Language: en
DOI: 10.47391/JPMA.1490
The aim of this study was to determine the frequency of different subtypes of acute myeloid leukaemia (AML) cases that presented in a tertiary care hospital of Karachi. It was a retrospective cross-sectional study, conducted in the hospital’s Oncology department. Data of patients admitted during 2018 was collected from the records. In this study, patients were included using the non-probable convenient sampling technique. Selected cases were classified according to the French-American-British (FAB) classification and data analysis was performed using the SPSS version 25.0. Among the 61 patients included in the study, 28 were males and 33 were females, with a male to female ratio of 1:1.2. The patients’ age ranged between 15 and 92 years and the mean age of diagnosis was 36.13± 15.5 years. M2 was the most common FAB subtype in 14(29.8%) patients, followed by M1 in 11(23.4%) patients. Myeloperoxidase (MPO) was positive in 44 (71.4%) of those cases.
Keywords: Acute myeloid Leukaemia (AML), French-American-British (FAB) classification.
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