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Role of surgery in multifocal glioblastoma

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Title: Role of surgery in multifocal glioblastoma

Authors: Syeda Kubra Kishwar Jafri , Syed Sarmad Bukhari, Muhammad Shahzad Shamim

Journal: Journal of Pakistan Medical Association

HEC Recognition History
Category From To
Y 2024-10-01 2025-12-31
X 2023-07-01 2024-09-30
X 2022-07-01 2023-06-30
X 2021-07-01 2022-06-30
X 2020-07-01 2021-06-30
W 2012-07-01 2020-06-30
X 2011-05-13 2012-06-30
Y 1900-01-01 2005-06-30

Publisher: Pakistan Medical Association.

Country: Pakistan

Year: 2022

Volume: 72

Issue: 3

Language: en

DOI: 10.47391/JPMA.22-021

Categories
Surgical Intervention (3) Multifocal Tumors (1) Neurosurgery (1650) Brain Tumors (37) Glioblastoma (5)

Abstract

The management of multifocal glioblastomas is a point of constant discussion amongst neuro-oncologists. Best outcomes in glioblastoma management come from gross total resection (GTR) followed by concomitant radiation and chemotherapy (CCRT). Multifocal disease is resistant to GTR. Conventional management of these lesion is usually biopsy only followed by CCRT. Recent evidence has shown that there may be some benefit to attempting GTR of the largest lesion whenever safe to do so.
Keywords: Glioblastoma multiforme; multifocal; radiotherapy; chemotherapy
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