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Abstract

Abstract: In this study, we evaluated the level of care given by our institution and to assess the non-compliance along with predictor for
non-compliance among osteosarcoma patients.
Materials and Methods: The included participants were proven for osteosarcoma after biopsy between January 2014 to December 2020.
Records were searched from Departmental Cancer Registry for details regarding treatment plans and follow-ups. The data of outcomes were
compared with the standard guidelines. Patients who did not attend follow-ups, surgery or chemotherapy were termed as non-compliant. The
patients or their next of kins were inquired about the factors behind non-compliance.
Results: 46 participants with 34 (74.9%) males and 12 (26.1%) females and a mean age of 19.7± 9.7 years were included. The prescribed
treatment plan was followed by 11 (23.91%) patients. Neoadjuvant and adjuvant chemotherapy were taken by 18 (39.13%) and 10 (21.74%)
candidates, respectively. Surgery was performed in 22(44.9%). The patients who did not received chemotherapy was attributed to affordability
(P=0.008) and patients’ or next to kins’ choices (P=0.02) while age (P=0.039), patients’ consent not given (78.3%; P=0.05), and stage II
(52.2%; P=0.048) were predictors of surgical non-compliance.
Conclusion: We conclude that the care deferred significantly from the guidelines regarding surgery and chemotherapy. Age, affordability, late
stage, and personal choices are the significant predictors for non-compliance for chemotherapy and surgery.