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Abstract

Objective: The categorization of sweat gland tumors has been inconsistent over time. These tumors, having varying potential formalignancy, may behave as indolent neoplasms while others can be highly metastatic. The characteristics of most of these tumors areoverlapping and the information of distinctive findings about these neoplasms is imperative. Traditionally, sweat gland tumors were classifiedas eccrine and apocrine only but recently, this has been found that several sweat gland tumors may exhibit eccrine and apocrine types both.Some tumors exhibit further complex features due to the existence of other differential appearances. This can be in the instance of apocrineneoplasms because of the close embryological link between apocrine glands, hair follicles and sebaceous glands and they can be classified asfollicular and/or sebaceous tumors. Cutaneous adnexal neoplasms are a diagnostic challenge, especially for tumors with sweat glanddifferentiation, due to a huge number of uncommon entities, designation of different terms to the identical tumor following to disagreementabout the taxonomy and nomenclature of such tumors. This review article provides updated information about various cancerous sweat glandneoplasms with emphasis on recent conclusions for the diagnosis and generalized therapy of such neoplasms.