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Oral Spindle Cell Carcinoma –Diagnosis Based on Immunohistochemical Interpretation


Article Information

Title: Oral Spindle Cell Carcinoma –Diagnosis Based on Immunohistochemical Interpretation

Authors: Syeda Asiya Butool, Ankit Natani, Betina Chandolia, Manas Bajpai

Journal: National Journal of Health Sciences

HEC Recognition History
Category From To
Y 2024-10-01 2025-12-31
Y 2023-07-01 2024-09-30
Y 2022-07-01 2023-06-30

Publisher: National Institute of Blood Disease Welfare Society

Country: Pakistan

Year: 2020

Volume: 5

Issue: 3

Language: en

Keywords: Head and NeckSpindle Cell VariantBiphasic tumorPseudocarcinomaSqamous cellDysplastic

Categories

Abstract

Abstract: Spindle Cell Carcinoma (SpCC) is a biphasic tumor. They are proven to be monoclonal dedifferentiated forms of conventional squamous carcinomas. It is a rare tumor which is infrequently observed in head, neck and in the aerodigestive tract. The tumor is aggressive and shows high frequency of recurrence and metastasis. It is an aggressive variant of squamous cell carcinoma which resembles a true sarcoma. It is a proliferation of spindle cells and squamous cells. For confirmation of diagnosis, immunohistochemistry is used. A Rare case of spindle cell squamous cell carcinoma in a 61 years old male in the tongue. The patient reported of rapidly growing lesion from six months with pain severe pain, dysphagia and difficulty in swallowing patient had history of chewing tobacco from past 35 years.


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