DefinePK

Abstract

Background: Diabetes has emerged as one of the major health care problems in Pakistan. It is also known that almost 50% of the people with diabetes remain undetected and some may even present with microvascular and macrovascular complications at the time of diagnosis. Diabetic nephropathy is a relatively common form of chronic renal disease.
Objective: The goal of the present research was to find the correlation between renal artery resistive index and renal function tests in individuals with type II diabetes.
Methods: This was a 9-month cross-sectional analytical study performed at Hamza Medicare Rahim Yar Khan in Pakistan, from April 2020 to December 2020. The research project comprised 60 people with type 2 diabetes mellitus who had been diagnosed with the disease for more than 5 years and had a HbA1c level of more than 6.5%. Patients had biochemical tests, a kidney examination, and a renal Doppler ultrasonography.
Results: Renal artery resistive index was increased in patients with high serum creatinine levels. Resistance index and serum creatinine had a positive correlation of r=0.438 (p<0.001). The correlation between RI and microalbuminuria was also positive, with r = 0.245 (p = 0.05). For r=-0.057 (p=0.663) there was a negative association between resistivity index and 24-hour urine protein. There was also a strong association between RI and HbA1c levels, with r=0.162 (p=0.217). correlation between RI and Duration of diabetes was significant with r=0.312 (p-value 0.015).
Conclusion: Therefore, it can be concluded that renal artery resistivity index assessed using duplex Doppler ultrasonography is a reliable method, which can be linked to the biochemical parameters of renal dysfunction in patients suffering from type 2 diabetes with diabetes and kidney disease