DefinePK

Abstract

INTRODUCTION:
Cardiovascular diseases represent the main cause of morbidity and mortality in patients with chronic kidney disease (CKD. Left ventricular hypertrophy (LVH) represents a key
feature to provide an accurate picture of systolic-diastolic left heart involvement in CKD
patients.
 
OBJECTIVE:
 
To  determine  the  frequency  of left ventricular diastolic  dysfunction  in  end  stage  renal disease patients on hemodialysis.
 
Material and Methods: Descriptive Cross Sectional was conducted at  Department of
Nephrology, Institute of Kidney Diseases Peshawar from 11th  July 2018 to 10th  January

All the patients were stabilized and after initial stabilization and treatment of these patients, written informed  consent  was  obtained  from  them.  Echocardiogram  was

performed by consultant cardiologist in order to look for the presence of LV dysfunction. LV  systolic  dysfunction  considered  depressed  when  left  ventricular  ejection  fraction (LVEF) was found less than 45%. Clinical and electrocardiographic evidences of valvular heart disease, heart failure (EF<50%) and myocardial ischemia were excluded from this study.
 
RESULTS:
 
As per frequencies and percentages for LVDD, 121 (87.68%) patients were recorded with
LVDD.
 
CONCLUSION:
 
In this study, we concluded that LVDD is a typical feature of CKD-related cardiomyopathy as LVDD and myocardial fibrosis are associated with mortality risk and cardiovascular events in CKD and ESRD as demonstrated by higher rates of sudden cardiac death in these patients.