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Abstract

Background:
Cystic fibrosis (CF) is a hereditary condition characterized by the buildup of mucus in the airways and subsequent respiratory difficulties. The present investigation, carried out between August 2022 and April 2023, examines the effects of chest physiotherapy on the well-being of a cohort of 110 individuals diagnosed with cystic fibrosis.
Objective:
The research specifically investigates the influence of this intervention on lung function, quality of life, and the management of symptoms.
Methodology:
A prospective cohort study was carried out at HMC Peshawar, strictly adhering to ethical guidelines. Lung function, quality of life (measured via CFQ-R), and respiratory symptom data were systematically collected.
Results:
Significant enhancements were seen promptly, as indicated by an average 7.8% augmentation in Forced Expiratory Volume in one second (FEV1) subsequent to a solitary session of chest physiotherapy. During the duration of the trial, a comprehensive examination revealed a consistent improvement in lung function, as shown by a significant increase in forced expiratory volume in one second (FEV1) from 65.3% to 74.6%. The quality of life, as measured by the CFQ-R, showed a statistically significant improvement of 12 points. There was a significant reduction in respiratory symptoms, such as coughing and difficulty breathing.
Conclusion:
Significant enhancements in pulmonary function were promptly noted subsequent to a solitary session of chest physiotherapy. The longitudinal analysis demonstrated a consistent and prolonged improvement in pulmonary function over the duration of the research. There was a substantial improvement in the quality of life, accompanied by a notable decrease in respiratory symptoms. The present research provides more evidence of the significant advantages of chest physiotherapy in the treatment of cystic fibrosis (CF), as shown by quantitative data that substantiates its immediate and enduring effects.