DefinePK

Abstract

Background: Atypical pulmonary metastases present a diverse range of radiologic findings in the lungs, deviating from the typical patterns of metastatic disease. These unique radiological characteristics play a pivotal role in their diagnosis and differentiation from other lung pathologies.
Objective: The goal is to show the various imaging patterns for pulmonary metastases from various primary malignancies.
Methodology: This study is a retrospective descriptive analysis in which we examined 30 cases of pulmonary metastasis originating from various primary malignancies. The study was conducted at the Radiology departments of Khyber Teaching Hospital, Peshawar and Hayatabad Medical Complex, Mardan, between July 2017 and August 2021. Our focus was on identifying and documenting the unique radiologic characteristics associated with metastases originating from different primary cancers.
Results: In our institution, we conducted an analysis of 30 cases of pulmonary metastases. Among these cases, we observed varying patterns of metastatic spread. Specifically, 4 (14%) cases were associated with Renal cell carcinoma, 2 (7%) cases with testicular germ cell tumours, 4 (13%) cases with thyroid cancer, 2 (7%) cases with osteosarcoma, 4 (13%) cases with GI tract adenocarcinoma, 3 (10%) cases with gynaecological malignancies, 1 (3%) case with femoral vein leiomyosarcoma, 4 (13%) cases with breast cancer, 1 (3%) case with lymphoma, and 5 (17%) cases with lung carcinoma. These cases exhibited a range of pulmonary metastatic patterns alongside the typical presentation characterized by multiple soft tissue density nodules.
Conclusion: The usual radiologic signs of lung metastasis are several spherical, variable-sized nodules and widespread interstitial thickening. It is challenging to diagnose lung metastases because of various patterns. Therefore, understanding the various pulmonary metastasis patterns from various primary aids helps in the early detection of metastases.
Keywords: Pulmonary Metastasis; Patterns; Atypical Radiologic Features.