DefinePK

Abstract

Deep vein thrombosis (DVT) usually originates in the deep-veins of the leg. Risk of developing pulmonary embolism (PE) is high if the thrombus extends above the knee. There is controversy whether DVT below the knee requires treatment. If the decision is made not to treat below knee DVT then the patient should be followed for signs of progression of the thrombus above the knee. Risk Factors: Major Trauma and Surgery (especially orthopedic surgery), Hyper-coagulation states including Cancer, Congestive Heart Failure (with or without myocardial infarction) Bed Rest Pregnancy and post-partum period Contraceptive pills especially above the age of 35 and in smokers.