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Abstract

Purpose: The purpose of this research was to assess the knowledge and practice of standard infection control precautions among staff nurses at Isra University Hospital in Hyderabad. Design/Methodology/Approach: This descriptive cross-sectional study was conducted from July to September 2024, 60 nurses were chosen for the study using non-probability convenience sampling. Data was collected using a standardized questionnaire, and IBM SPSS Statistics Version 23 was used for analysis. Results: According to the findings, 38.3% of participants were female and 61.7% were male. The majority of staff nurses have good knowledge of infection control precautions; 85% of them recognize the standard precautions for all patients. However, there were gaps in the practices, as only 68% of respondents acknowledged the need for isolation precautions, and fewer participants followed protocols like wearing gloves during patient assessments (55%) and blood collection (45%). Conclusion: The study showed that staff nurses had good knowledge and practice of basic standard infection control precautions, but observed moderate compliance with specific practices, especially contact and isolation precautions. The findings of this research suggest that targeted training is required to close compliance gaps, improve patient safety, and improve general measures to prevent infections.