DefinePK

Abstract

The study is based on succinylcholine which is a routine muscle relaxant for pediatric patients. Rocuronium is newer non depolarizing muscle relaxant. The objective of this study was to assess time, course and duration of both relaxants as well as intubation conditions. This study was blind and randomized in nature and conducted to test the intubating conditions with two separate kind of muscle relaxants in 50 ASA grade I and II pediatric patients who fall in age category of 2 to 6 years who undergone surgery of less than half an hour. Patients were anaesthetized with injection rocuronium 0.9 mg/kg i.v. or with injection succinylcholine 1.5 mg/kg after injection fentanyl 1ug/kg and injection thiopentone 5 mg/kg. The assessment of Neuromuscular blockade was conducted with twitch response of adductor pollicis longus after supra-maximal stimulation of ulnar nerve. We assessed Tracheal intubating conditions using the blinded anesthetist after 1 month and every 15 seconds till patient got intubated. The time of onset and percentage of neuromuscular blockage was also assessed.