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Abstract

The present study investigated the relationship among migraine severity, cognitive impairment and health-related quality of life in migraine patients. The sample for this cross-sectional study consisted of 152 migraine patients, age ranging from19 to 35 years. A convenient sampling applied that enabled a wider range of migraine patients to participate. Self-report measures including demographic questionnaire, Migraine Severity Scale (MIGSEV), Cognitive Impairment Scale and Health-Related Quality of Life Short Form (SF-36) were used to assess the study variables. The correlation analysis demonstrated a positive relationship between migraine severity, cognitive impairment and health-related quality of life (physical functioning, role limitation due to physical health, role limitation due to emotional problems, energy/fatigue, emotional well-being, social functioning, pain and general health) have a relationship with the prevalence of migraine severity and cognitive impairment in migraine patients. Regression analysis also indicated that migraine severity and cognitive impairments positively predicted health-related quality of life in migraine patients. Mediation analysis showed that cognitive impairment mediated the relationship between migraine severity and health-related quality of life in migraine patients.