DefinePK

Abstract

Stevens–Johnson Syndrome (SJS) and Toxic Epidermal Necrolysis (TEN) are rare but potentially life-threatening mucocutaneous reactions most often triggered by medications such as antibiotics or anticonvulsants. Acetaminophen, a commonly used antipyretic in pediatric practice, is an uncommon but documented cause. We present a rare case of SJS-TEN overlap in a 2-year-old boy following acetaminophen administration, involving approximately 25% of the body surface area. Prompt discontinuation of the offending drug, coupled with supportive care and early corticosteroid therapy, led to complete recovery without complications. This case underscores the importance of clinical vigilance and timely intervention, even with routinely prescribed medications in children