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Abstract

Neurofibromas, typically associated with neurofibromatosis, are benign tumors originating from nerve sheaths. Solitary giant neurofibromas, particularly those emerging from the lower limbs, are relatively uncommon. Here, we present a case of a giant neurofibroma located in the right thigh of a 35-year-old female patient who presented with a 5-year history of a gradually enlarging swelling in the anterior aspect of the right thigh, diagnosed as neurofibroma following MRI and Trucut biopsy. Local excision was performed, with uneventful postoperative recovery. This case underscores the clinical importance of considering neurofibroma in the differential diagnosis of thigh swellings and highlights the efficacy of local excision in managing such lesions