DefinePK

Abstract

Burns are a worldwide public health issue that poses significant obstacles to both the economy and public health. Shock, multiple organ failure, systemic infection, and even death are common outcomes of severe burns. Because standard dressings only serve one purpose and have several negative consequences, they have not been able to satisfy the growing need for burn wound therapy. In this regard, electrospinning presents a promising avenue for developing cutting-edge wound dressings that encourage wound healing and guard against infection. With its large specific surface area, high porosity, and similar to natural extracellular matrix (ECM), electrospun nanofibers can load drugs and accelerate wound healing. It offers a potentially effective way to control and treat burn injuries. This review article introduces the concept of burn and the types of electrospun nanofibers, and then summarizes the polymers used in electrospun nanofiber dressings. The medications filled with electrospun burn dressings (plant extracts, small molecule medications, and nanoparticles) are finally compiled. Promising elements are suggested for the development of commercial electrospun burn treatments