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Effect of Vitamin D in Dental Implants Osseointegration – A Randomized Controlled Trial


Article Information

Title: Effect of Vitamin D in Dental Implants Osseointegration – A Randomized Controlled Trial

Authors: Atif Iqbal, Noor Ul Wahab, Nabeel Baig, Afifa Razi, Komal Shahzad, Dr Hafiz Mujtaba Hussain

Journal: Annals Abbasi Shaheed Hospital & Karachi Medical & Dental College

HEC Recognition History
Category From To
Y 2023-07-01 2024-09-30
Y 2022-07-01 2023-06-30
Y 2021-07-01 2022-06-30
Y 2020-07-01 2021-06-30

Publisher: Karachi Medical and Dental College

Country: Pakistan

Year: 2024

Volume: 29

Issue: 4

Language: en

DOI: 10.58397/ashkmdc.v29i4.981

Keywords: Vitamin D DeficiencyDental implantsimplantation,ISQ valueOsseo-integration,Vitamin D supplementation.

Categories

Abstract

Objective: To assess the impact of vitamin D supplementation on osseointegration success rates in dental implant patients at a tertiary care hospital.Methods: The randomized control trial included patients aged 18 to 45 years, either gender with Vitamin D insufficiency undergoing dental implant procedures and had vitamin D insufficiency. Exclusion criteria was prior bone regenerative therapy, arthritis, periodontal disease, bleeding disorders, poor oral hygiene, uncontrolled hypertension and diabetes mellitus, severe vitamin D deficiency, chronic renal disease, use of proton pump inhibitors, pregnant women. This was a and patients were enrolled via non probability consecutive sampling. Participants were equally divided into two groups: Group Areceived a daily oral intake of 5000 IU Vitamin D3 for 12 weeks, while Group B received a placebo (vitamin E 400mg). Osseo-integration was evaluated at three months using radiographic and clinical assessments with Ostell (ISQ). Additionally, serum Vitamin D levels were measured pre-operatively and post-operatively at 3 months interval post implant placement. Data analysis was performed using SPSS version 23.00.Results: The median ISQ at three months was notably higher in Group A (Vitamin D supplement) compared to Group B (placebo), with values of 71 vs 65 ISQ (p=0.001). Moreover, the median Vitamin D levels at three months were significantly elevated in Group A compared to Group B (p=0.001). The mean age of the study sample was 33.71±7.84 years. The study found that vitamin D levels were significantly higher in Group A compared with Group B at three months (p=0.001) that suggesting that the supplementation was effective in elevating Vitamin D levels.Conclusion: The study concludes that Vitamin D supplementation significantly improves osseointegration of dental implants. It emphasizes the importance of targeted vitamin D supplementation in optimizing implant success.


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