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Multifaceted approaches to promoting the growth potential in small-for-gestational-age infants and their clinical relevance


Article Information

Title: Multifaceted approaches to promoting the growth potential in small-for-gestational-age infants and their clinical relevance

Authors: Lijuan Si, Jing Guo, Wenlong Du, Simeng Zhao, Jing Li

Journal: Pakistan Journal of Medical & Cardiological Review (PJMS)

HEC Recognition History
Category From To
Y 2024-10-01 2025-12-31

Publisher: Intellect Educational Research Explorers

Country: Pakistan

Year: 2025

Volume: 41

Issue: 7

Language: en

DOI: 10.12669/pjms.41.7.11010

Keywords: Insulin ResistanceSmall for gestational ageMDICatch-up GrowthZ-scorePDI

Categories

Abstract

Objective: To investigate the multifaceted approaches to promoting growth potential in small-for-gestational-age (SGA) infants and their clinical relevance.
Methods: This was a retrospective study. A total of 196 SGA infants who were born in the Department of Obstetrics at Baoding Maternal & Child Health Hospital from February 2020 to February 2024 were selected as the study subjects and were divided into the control group (n=98) and the catch-up group (n=98) according to different nursing approaches. Specifically, the clinical value was investigated using the various development index, and maternal anxiety and depression scores.
Result: No significant differences were observed in body weight, height, WAZ, and HAZ between the 2 groups at 3 ~ 9 months of corrected age (P > 0.05), while the body weight, height, WAZ, and HAZ in the catch-up group were greater than those in the control group at 12 ~ 24 months of corrected age, with significant differences (P < 0.01). Meanwhile, at 24 months of correction age, PDI, MDI, FBG and Homa-IAI indexes in the catch-up group were higher than those in the control group, while FINS, Homa-IR, HBCI and anxiety and depression indexes were lower than those in the control group, with statistical significance (P<0.01).
Conclusion: Early interventions in SGA infants with appropriate growth potential can achieve catch-up growth and prevent side effects of overnutrition-induced insulin resistance.
doi: https://doi.org/10.12669/pjms.41.7.11010
How to cite this: Si L, Guo J, Du W, Zhao S, Li J. Multifaceted approaches to promoting the growth potential in small-for-gestational-age infants and their clinical relevance. Pak J Med Sci. 2025;41(7):1881-1886. doi: https://doi.org/10.12669/pjms.41.7.11010
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


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