DefinePK

Abstract

Diabetes mellitus is a chronic condition in which the blood glucose level gets abnormally higher than the normal range. It usually occurs due to insufficient insulin production or maybe because the body is unable to utilize insulin. To treat this metabolic disorder, oral and parenteral treatment methods are utilised, but these methods are quite painful, have poor patient compliance, and have a risk of infection. However, instead of injection and oral drug delivery, TDD can be preferable as it is less painful, provides better patient compliance, and has a sustained drug release mechanism. Moreover, it shows higher bioavailability as it bypasses the first-pass effect. Several studies and research have already been conducted on developing and improving the TDD system for diabetes management. In this research work, a comprehensive review of past studies has been presented to focus on the use of the transdermal drug delivery system (TDD) as an effective treatment method for diabetes mellitus. The aim is to highlight the transdermal drug delivery treatment and procedures that have been implemented in diabetes management.