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Clinical Outcomes and Frequency of Electroencephalographic Abnormalities in Patients with First Unprovoked Seizure in a Tertiary Care Hospital: A Cross-Sectional Study


Article Information

Title: Clinical Outcomes and Frequency of Electroencephalographic Abnormalities in Patients with First Unprovoked Seizure in a Tertiary Care Hospital: A Cross-Sectional Study

Authors: Rabbiyah Masood, Madiha Malik, Maimoona Tanwir Rana, Samrat Habib, Ali Nawaz, Taha Habib

Journal: Pakistan Journal of Health Sciences (PJHS)

HEC Recognition History
Category From To
Y 2024-10-01 2025-12-31
Y 2023-07-01 2024-09-30
Y 2022-07-01 2023-06-30

Publisher: Lahore Medical Research Center

Country: Pakistan

Year: 2025

Volume: 6

Issue: 6

Language: en

DOI: 10.54393/pjhs.v6i6.2363

Keywords: ElectroencephalogramSeizure RecurrenceUnprovoked SeizureEpilepsy Diagnosis

Categories

Abstract

Epilepsy is a common medical condition that has widespread neurobiological, cognitive, psychological, and social consequences. Recurrent seizures are a common feature of this illness. Individuals experiencing their first unprovoked seizure generally present with Electroencephalographic (EEG) abnormalities, which might reflect a broad range of underlying neurophysiological changes. Identifying and measuring these abnormalities is critical for differentiating between epileptic and non-epileptic seizures, determining suitable treatment techniques, and predicting future seizure risk. Objective:  To determine the frequency of abnormal EEG in patients presenting after first unprovoked seizures. Early detection of these abnormalities will better guide for better management and to predict recurrence. Methods: The study was a six-month cross-sectional retrospective held at the Punjab Institute of Neurosciences, Lahore, Pakistan from January 2024 to June 2024. This study employed the non-probability consecutive sampling method. The study included 95 patients who met the inclusion and exclusion criteria. Previous medical data included a complete patient history, clinical examination, and EEG results. Data were then analyzed using SPSS version 21.0. Results: Out of 95 patients, 52.63% were male and 47.37% were female, averaging 52.6 + 5.6 years. A total of 46 individuals (48.42%) had abnormal EEG irrespective of age, gender, length of symptoms, and awareness of symptoms. Conclusion: This study concluded that EEG abnormalities are highly frequent among individuals following their first unprovoked seizure. 


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