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Histopathological and Radiological Findings in Nasolabial Cysts


Article Information

Title: Histopathological and Radiological Findings in Nasolabial Cysts

Authors: Vijay Kumar Khatri, Syed Muhammad Moosa Raza, Sabhagi Kumari, Syed Mohsin Ahmed Rizvi, Saima Batool Jaffri, Fiza Irfan, Ali Muntazir Naqvi

Journal: Pakistan Journal of Health Sciences (PJHS)

HEC Recognition History
Category From To
Y 2024-10-01 2025-12-31
Y 2023-07-01 2024-09-30
Y 2022-07-01 2023-06-30

Publisher: Lahore Medical Research Center

Country: Pakistan

Year: 2025

Volume: 6

Issue: 6

Language: en

DOI: 10.54393/pjhs.v6i6.3117

Keywords: Nasolabial cystsradiological featuresHistopathological FeaturesBone Remodelling

Categories

Abstract

Nasolabial cysts are relatively rare, non-odontogenic soft tissue cysts that are usually found in the nasolabial fold, just beneath the nasal ala. Objectives: To analyse the clinical, histopathological, and radiological features of nasolabial cysts and evaluate their association with symptom duration, cyst size, and bone remodelling. Methods: This retrospective case series study included 10 patients diagnosed with nasolabial cysts. Patient data, including age, gender, ethnicity, cyst size, location, and duration of symptoms, were collected. Radiological assessments focused on bone remodelling and scalloping through computed tomography (CT) scans. Histopathological examination of excised cysts assessed the type of epithelial lining. Statistical analysis was performed to evaluate associations between cyst characteristics, symptom duration, and radiological findings, using Pearson’s correlation and Chi-square tests. Results: The mean age of patients was 44.9 years, with a male predominance (60%). A significant association was found between longer symptom duration and the presence of bone changes on CT (p=0.03), and a moderate positive correlation existed between cyst size and symptom duration (r=0.32, p=0.009). Conclusions: It was concluded that nasolabial cysts can lead to bone remodelling when symptoms persist for extended periods. Early diagnosis and treatment are critical in preventing complications. Further research is needed to explore minimally invasive treatment approaches for managing nasolabial cysts.


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