DefinePK

Abstract

The worldwide increase in the misuse of new synthetic psychoactive drugs has created unsolvable problems for forensic toxicologists, healthcare workers, and law enforcement. Emerging synthetic drugs, or new psychoactive substances (NPS) can include synthetic cannabinoids, cathinones, opioids, or designer benzodiazepines and are difficult to characterize due to their rapid development, chemical diversity, and potent pharmacological effects. There have been various reviews assessing NPS with respect to their classification and pharmacokinetics, detection methods, and analytical issues. They claim that the importance of toxicovigilance and early warning systems is important in detecting and managing the effects of new synthetic drugs, as well as the need for However, to improve forensic detection and control methods, multidisciplinary approaches must be adopted and implemented, especially in Pakistan. The evolution of drugs continues, and they need to be managed collectively, and at a minimum consistently, around the globe. Just as if there is a need to identify opportunities to fill these gaps in most aspects of research, legal control methods, or laboratory capacity, I trust that the piece will contribute to the expanding body of knowledge around how we may most effectively manage their forensic toxicology.