DefinePK

Abstract

HCC is the fifth commonest cancer worldwide; with more than one million new cases diagnosed each year.1The incidence of HCC varies widely, being most common in Southeast Asia sub-Saharan Africa and much less in North America and Western Europe. 2 Annual incidence in Pakistan is 8/100,000.3 Hepatitis C and B have been found to be the leading causes in Pakistan .4, 5, 6.  In developing countries, HCC is a leading cause of death and accounts for between 60% and 90% of all primary liver malignancies.7