DefinePK

Abstract

Cloud Point Extraction (CPE) technique depends on the preconcentration of material in aqueous medium, and it is known that the surfactants in the mentioned technique could concentrate these materials. The CPE technique receives great attention because of the simplicity and speed of the method, and the extraction process is beneficial by improving the experimental conditions by adjusting the acidity function, temperature, type of electrolyte, extraction time and surfactant concentration. The surfactant leads to the phase separation of the so-called surfactant-rich phase and the surfactant aqueous phase. The comparison of the maximum temperature with the critical temperature is called the cloud point temperature which will be Then the substance to be analyzed is concentrated and the preconcentration factor is high. This article describe the applications of CPE method in the determination of different drugs using deferent reactions and various reagents.