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Title: The link between migraine and eye pain: a review of current evidence
Authors: Mujeeb Ur Rehman Parrey, Maha M Abdul-Latif, Muhammad Omer Afzal Bhatti, Hafiz Osman Ibnidris Almisbah, Ahmed Hamad Ahmed Sulaiman, Omaima A Hamid MD, Mohammed M. Ismail
Journal: Anaesthesia, Pain and Intensive Care
Publisher: Faculty of Anaesthesia, Pain and Intensive Care, AFMS
Country: Pakistan
Year: 2025
Volume: 29
Issue: 3
Language: en
Keywords: quality of lifeMigraineDry eye diseaseTrigeminal NeuralgiaOcular manifestationsPathophysiologydiagnostic challengesEye PainCluster headache
Eye pain is a frequent and distressing symptom in individuals with migraines, yet it remains an underexplored aspect of migraine pathology. This review consolidates current knowledge on the association between eye pain and migraines, covering pathophysiological mechanisms, clinical features, differential diagnoses, and management approaches. A thorough analysis of existing literature indicates that migraine-related eye pain is multifactorial, involving neural, vascular, and sensory pathways. Additionally, this review underscores the need for further research to refine diagnostic criteria and enhance treatment strategies for patients experiencing ocular discomfort during migraine episodes.
Key words: Eye Pain; Migraine; Cluster Headache; Pathophysiology; Diagnostic Challenges; Ocular Manifestations; Trigeminal Neuralgia; Dry Eye Disease; Quality of Life
Citation: Parrey MUR, Abdul-Latif MM, Bhatti MOA, Almisbah HOI, Sulaiman AHA, Omaima A Hamid OA, Ismail MM. The link between migraine and eye pain: a review of current evidence. Anaesth. pain intensive care 2025;29(3):681-688. DOI: 10.35975/apic.v29i3.2772
Received: February 05, 2025; Revised: February 25, 2025; Accepted: March 06, 2025
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