DefinePK

Abstract

Background: the most common bariatric procedure now is laparoscopic sleeve gastrectomy (LSG). Symptoms originating in the upper gastrointestinal tract (UGI) are common after LSG due to the altered stomach architecture.
Objective: Finding out how LSG affects GERD is the goal of this study. Also reviewing of the improvement or worsening of reflux disease in patients after LSG, and the development of new disease in healthy persons.
Methods: The 70 participants in this prospective study all had LSG. Evaluation specific to GERD was done prior to surgery. Patients had UGI endoscopies and stool samples tested for Helicobacter pylori before surgery to rule out any abnormalities. It was necessary to do postoperative UGI endoscopy in order to classify the findings and establish a connection between the evaluated symptoms and UGI issues.
 Results: The number of patients displaying upper gastrointestinal symptoms increased significantly after a 6-month follow-up; however, there was no significant change in the percentage of patients who developed GERD (p < 0.01). Discomfort in the stomach has increased dramatically. Significant vomiting and dysphagia are among the new and ongoing symptoms. Six months after surgery, there was a link between vomiting and hiatus hernia, and there was a strong relationship between GERD and hiatus hernia overall. Preoperative GERD symptoms and H. pylori infection were significantly associated with each other and with abnormalities of the UGI.
Conclusion: Ultimately, most very obese patients with preoperative GERD have worsening symptoms after LSG, and "de novo" reflux is quite uncommon. After a median follow-up of 6 months after LSG, dyspepsia, not GERD, became the most common complaint. Because GERD was present in all patients who vomited, there was a strong correlation between hiatus hernia and GERD.