DefinePK

Abstract

Background: Pain and urinary symptoms affecting the prostate and/or other areas of the male reproductive system are symptoms of chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS).
Objective: The safety and acceptability of cooled transurethral microwave thermotherapy (TUMT) for chronic prostatitis/chronic pelvic pain syndrome were examined in this prospective feasibility research.
Methods:There were 76 male patients were presented in this study.Patients who had an NIH-CPSI pain score of 8 or higher and had symptoms that persisted for more than three months prior to treatment were randomly assigned to either cooled TUMT at around 55°C or cooled TUMT at about 70°C intraprostatic temperatures. Outcomes were assessed.
Results: The mean age of the patients was 29.6±4.17 years with mean weight 71.5±7.28 kg. Mean duration of symptoms was 23.10±8.73 months. After 12 months, the mean NIH-CPSI score showed significant improvements in total score (22.3± 5. vs. 10.3±9.1), pain score (12.3±3.4 vs. 3.7±6.5), quality-of-life impact score (6.9± 2.9 vs.2.7 ± 3.5; all P <0.0002), and urinary score (5.4±1.7 vs.2.0 ± 1.1; P = 0.0077).
Conclusion: For chronic prostatitis that has proven difficult to treat, cooled TUMT provided better outcomes. To better assess the effect on fertility and long-term durability, lengthier follow-up and a bigger experiment are necessary