DefinePK

DefinePK hosts the largest index of Pakistani journals, research articles, news headlines, and videos. It also offers chapter-level book search.

Integration of Genomics and Bioinformatics for Personalized Medicine: Predicting Drug Responses and Optimizing Treatment Plans


Article Information

Title: Integration of Genomics and Bioinformatics for Personalized Medicine: Predicting Drug Responses and Optimizing Treatment Plans

Authors: Shankar Lal, Saeed Ahmed, Tabeel Tariq Bashir , Avesh Kumar , Muhammad Furquan

Journal: Journal of Computing & Biomedical Informatics

HEC Recognition History
Category From To
Y 2023-07-01 2024-09-30
Y 2022-07-01 2023-06-30

Publisher: Research Center of Computing & Biomedical Informatics

Country: Pakistan

Year: 2025

Volume: 9

Issue: 1

Language: en

Keywords: GenomicsBioinformaticspersonalized medicinePharmacogenomicsMachine Learning in EEGDrug Response Prediction

Categories

Abstract

The integration of genomics and bioinformatics has revolutionized individualized medicine by enabling precise prediction of medicine responses and optimization of personalized treatment plans. This paper reviews current methodologies in genomic data accession, bioinformatics channels and multi omics data integration to identify clinically practicable biomarkers. We discuss machine literacy models that work high- dimensional genomic and clinical data to prognosticate remedial efficacy and adverse medicine responses with high accuracy. Clinical operations across oncology, psychiatry and cardiovascular drug demonstrate significant advancements in patient issues when treatment opinions are guided by genomic perceptivity. Also, we address critical ethical, legal and social counteraccusations, emphasizing the significance of data privacy, informed concurrence and indifferent access to genomic technologies. Challenges similar as data diversity, limited population diversity and clinical implementation walls are anatomized, alongside unborn directions including real- world data integration, advanced single- cell genomics and AI interpretability. This comprehensive approach underscores the transformative eventuality of genomics and bioinformatics in advancing substantiated healthcare and perfecting treatment efficacy while promoting responsible and indifferent use.


Paper summary is not available for this article yet.

Loading PDF...

Loading Statistics...