DefinePK

Abstract

This research aims to analyze the impact of two pesticides, Chlorpyrifos and fosetyl-aluminum, on the hematological and biochemical profiles in the declining population of Japanese quail (Coturnix japonica) and situate its output within a wider field of ecological concerns and environmental education. The findings revealed profound and significant alterations of target mediators in a dose- and time-related manner. A total of 30 adult quails were divided into five groups: (G1) was treated as the control group, (G2) and (G3) were administered low doses, while (G4) and (G5) received high doses of Chlorpyrifos and fosetyl-aluminum, respectively. Each bird in the treated groups received an oral dose of 10 ml daily through a crop tube. After 10 days of exposure to both Chlorpyrifos and fosetyl-aluminum, significant changes were observed in urea, creatinine, ALT, ALP, WBC, and MCHC, with additional changes in bilirubin, MCV, and MCH appearing after 15 and 20 days. These physiological changes underscore the other effects of pesticides on general ecology since their use has ripple effects throughout trophic levels, affecting overall ecosystems. In addition to fundamental benefits from the cross-disciplinary analysis of the effects of toxicological damage on wildlife, the focus is on integrated, education-based approaches to advancing sustainable practices. The study also proposes that incorporating toxicological data into environmental education curricula will improve ecological understanding and the ability of communities to make wise decisions about the usage of pesticides.