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Influence of Anti-Endometrial Antibodies on the Activity of Inflammatory Processes in Patients with Genital Endometriosis

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Title: Influence of Anti-Endometrial Antibodies on the Activity of Inflammatory Processes in Patients with Genital Endometriosis

Authors: Sevinj Sevdimaliyeva, Hicran Bagirova

Journal: International journal of gynecology, obstetrics and neonatal care

HEC Recognition History
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Publisher: Cosmos Scholars Publishing House

Year: 2019

Volume: 6

Issue: 1

Language: en

Keywords: cytokinesinflammation.Genital endometriosisTNF-αAutoimmune antibodies

Categories
Cytokines (27) Medicine (22336) Gynecology (4800) Inflammation (472) Immunology (7543)

Abstract

Background: Genital endometriosis is characterized with the problems of immune homeostasis. The aim of present study was to determine the correlation between autoimmune and inflammation mediators in women with genital endometriosis.Material and methods: 100 reproductive age women with genital endometriosis were included in present study. We have determined the levels of TNF-α as anti-inflammatory cytokine and antiendometrial antibodies (AEA) in peripheral blood of women by standard ELISA method.Results: It was detected statistically significant positive correlation between AEA and TNF-α in women with genital endometriosis (p<0.05).Conclusion: Increased inflammation stimulates the synthesis of autoimmune antibodies in women with genital endometriosis.

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