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Abstract

The corpus callosum is the main transverse tract of fibers that connects the two cerebral hemispheres. In rare conditions an absence of fusion of the main commissural pathway connecting the cerebral hemispheres is observed. This malformation develops in utero and is classified as partial and complete agenesis or hypoplasia of corpus callosum. The condition is found in 3 to 7: 1000 live births. Fetal ultrasound (US) is first-line modality in evaluating corpus callosum by 18-20 weeks of gestation. Fetal magnetic resonance imaging (MRI) is useful for exact assessment of the degree of malformation as well as for detecting frequently associated anomalies. This pictorial review aims to present the role of fetal MRI as a valuable adjunct to US in various abnormalities of corpus callosum in fetuses, which is an important issue for prognostic counseling.