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Abstract

Hepatocellular carcinoma (HCC) is the fifth commonest cancer worldwide. Vascular invasion of the portal vein is one of the most important prognostic factors for survival in HCC patients and the prognosis is generally poor. The optimal treatment for patients with HCC and portal vein tumour thrombus (PVTT) remains controversial. Although many therapeutic options have been proposed, surgical resection is the only hope of cure for such patients.We present the case of a 74-year-old man diagnosed with a single HCC nodule with portal thrombosis in the right hepatic lobe in the setting of HCV-related liver cirrhosis. After a first approach with a loco-regional treatment not tolerated by the patient, a right hepatectomy proved the best option. One year later the patient is still free from disease.