DefinePK

Abstract

The assessment of antifungal potential of the aqueous and methanol extracts of sun-dried leaves of Cassia alata was investigated by testing the extracts against some fungi Candida albicans, Trichophyton mentagrophyte, Aspergillus niger and Penicillium using the Agar cup plate method. The Minimum Inhibitory Concentration MIC of the aqueous extracts against susceptible test organism was determined using the Agar dilution method. The results showed that the plant part can be used to treat infections caused by fungi Candida albicans, Trichophyton mentagrophyte and Aspergillus niger which were susceptible. However, results showed that C. alata extract has no effect on Penicillium. The in vitro findings justify the use of the extract of Cassia alata in traditional medicine practice for the treatment of some external skin and fungal infections. Cassia alata has shown to be a very versatile plant and can be a viable alternative as an antifungal agent.