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Abstract

The Integrative Weaning Index (IWI) is a multidimensional tool designed to measure the readiness of patients for extubation and weaning from mechanical ventilation. It encompasses various physiological, clinical, and ventilatory parameters that make for a more holistic assessment of a patient's readiness to transition off mechanical support. The IWI aims to reduce both premature extubation and prolonged ventilation, thus minimizing the complications associated with both. In this regard, it helps to decrease resource utilization and morbidity in patients. The index combines variables such as respiratory mechanics, oxygenation status, cardiovascular stability, and neurological function into a standardized score. It is most beneficial in intensive care where decisions need to be timely and evidence-based. The IWI has been shown to have potential for successful extubation prediction, improvement of clinical decision-making, and optimization of the weaning process, providing a valuable tool for clinicians managing mechanically ventilated patients.  
Objectives 
To assess the criteria used in the integrative weaning index for the prediction of successful weaning from mechanical ventilation.  
Methods 
The IWI criteria were fully evaluated, taking into consideration physiological, clinical, and ventilatory parameters. It involved respiratory mechanics, oxygenation status, cardiovascular stability, and neurological function.  
Results 
The results show that the IWI criteria could predict successful extubation and weaning outcome. The index revealed good sensitivity and specificity in pointing to the readiness of the patients for weaning.  
Conclusion 
The validity and reliability of the criteria in the Integrative Weaning Index are confirmed through evaluation, which predicts successful weaning from mechanical ventilation. It can be a useful tool for clinicians in intensive care settings to optimize decisions for weaning and thus improve patient outcomes