DefinePK

DefinePK hosts the largest index of Pakistani journals, research articles, news headlines, and videos. It also offers chapter-level book search.

COMPREHENSIVE INSIGHTS INTO HYPERCHOLESTEROLEMIA: PATHOPHYSIOLOGY, GENETICS, AND THERAPEUTIC ADVANCES


Article Information

Title: COMPREHENSIVE INSIGHTS INTO HYPERCHOLESTEROLEMIA: PATHOPHYSIOLOGY, GENETICS, AND THERAPEUTIC ADVANCES

Authors: Saira Asghar, Sumera Mushtaque, Rabia Iqtadar, Muhammad Azam

Journal: The Research of Medical Science Review

HEC Recognition History
Category From To
Y 2024-10-01 2025-12-31

Publisher: Innovative Education Research Institute

Country: Pakistan

Year: 2025

Volume: 3

Issue: 9

Language: en

Keywords: Familial Hypercholesterolemiacholesterol metabolismLipid-Lowering TherapiesGenetic and Molecular Mechanisms

Categories

Abstract

A serious health issue that raises the danger of cardiopathy and blow is hypercholesterolemia. This review article offers a thorough summary of the several hypocholesterolaemia drugs that assist lower blood cholesterol levels, such as fibrates, statins, and plant-based remedies. We look at the biochemical routes and mechanisms of action of these drugs, as well as their efficacy, safety, and possible adverse effects. Managing hypercholesterolemia, a disorder that can cause serious health issues, requires an understanding of these treatments. Healthcare providers and people can lower the risk of related health problems and manage cholesterol by investigating the most recent research and treatment choices. The most recent studies on new treatments, including as gene therapies and innovative lipid-lowering medications, are also covered in this review. We also go over how genetic testing and biomarkers can be used to classify those who are vulnerable of hypercholesterolemia and help guide treatment choices. This goal of this narrative review is to help patients and healthcare professionals to make educated decisions about cholesterol management and lower the risk of related cardiovascular complications by offering a thorough overview of the available treatment options and management strategies for hypercholesterolemia


Paper summary is not available for this article yet.

Loading PDF...

Loading Statistics...