DefinePK

Abstract

Introduction: Many traditional surgical intervention techniques have been superseded by endourological procedures in recent years.  The primary factor contributing to surgeons' predilection for these surgical intervention techniques is their minimally invasive nature. This study was done to compare the outcome of Open surgery versus Laparoscopic surgery in patients undergoing nephrectomy. Study design: Randomized controlled trial. Study Period: November 23, 2024, to May 22, 2025. Methodology: There were 60 patients, of either gender, undergoing nephrectomy, ranging in age from 16 to 65.  Patients with severe coagulopathies (INR>1.5), chronic renal failure were not included.  The open approach was used to operate on patients in group A. Patients in group B had laparoscopic surgery performed on them. With the researcher's help, a single surgical team completed every procedure. Operative time was noted. Patients were then moved to post-operative wards and monitored until they were discharged. The length of hospital stay was recorded. Findings: Groups B and A in my study had average operational times of 111.23 ± 12.98 and 86.13 ± 9.58 minutes, respectively.  Group A's mean hospital stay was 2.46 ± 0.81 days (p-value = 0.0001), whereas Group B's was 1.90 ± 0.80 days.   3.33% of patients in laparoscopic and 13.33% of patients in open group, respectively, suffered bleeding, per my research (p-value = 0.161). Wound infections affected 3.33% of patients in laparoscopic group and 13.33% of patients in open group (p-value = 0.161). Organ damage was present in 0.0% of patients in laparoscopic group and 6.67% of patients in open group (p-value = 0.150). Conclusion: This study came to the conclusion that, for patients having nephrectomy, laparoscopic surgery produces better results than open surgery.