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Abstract

Objectives: Neonatal supraventricular tachycardia (SVT) presents with a wide range of clinical manifestations, and although various combination therapies exist, no standardized guidelines specify preferred drug regimens. This study aimed to identify trends in the clinical spectrum and management of SVT in neonates.
Methodology: This retrospective observational study was conducted at the University of Child Health Sciences and Children’s Hospital Lahore from January 2023 to December 2024. Following Institutional Review Board (IRB) approval, all neonates diagnosed with SVT via electrocardiography were included. Data were analyzed using SPSS version 27. Numerical variables were expressed as mean ± standard deviation (SD), while categorical variables were presented as frequencies and percentages. Patients were categorized into Group A and Group B based on echocardiographic findings. Chi-square and independent t-tests were applied, with a p-value <0.05 considered statistically significant. Recurrence and survival rates were measured as outcome variables.
Results: A total of 15 neonates were included in the study, with a mean age of 15.3 days. Among them, 66.7% were male, and the average gestational age was 37.33 weeks. Congenital heart disease (CHD) was identified in 33.7% of cases, with secundum atrial septal defect (ASD) being the most common anomaly. Various treatment strategies, including amiodarone and adenosine, were administered based on the neonates’ cardiac profiles. A recurrence-free outcome was observed in 88.89% of neonates with actively engaged families.
Conclusion: Combination therapy was primarily required in neonates with CHD. Family-centered care significantly improved disease outcomes, emphasizing the importance of parental involvement in neonatal management.