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Abstract

Non-specific orbital inflammation (NSOI) is a complex diagnosis marked by inflammation of ocular tissues without an identifiable etiology. This case report describes a 37-year-old female with recurrent left-sided NSOI. Her early presentation included pain, proptosis, chemosis, and limited ocular movements. Imaging showed edema of the left optic nerve, hypertrophy of the extraocular muscles, enlargement of the lacrimal gland, and periorbital soft tissue edema. Although she initially exhibited a positive response to high-dose intravenous corticosteroids, her symptoms reemerged during the tapering process, requiring extended oral corticosteroid treatment. This case highlights the significance of a multidisciplinary approach, personalized treatment, and additional study into the fundamental processes and optimal management of this condition.