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Title: Neurobehavioral effects following vinegar administration in male Albino Wistar Rats
Authors: Lubna Anis, Irfan Sajid, Shoaib Ahmed, Hafsah Khan, Roshan Jahan Ara, Muhammad Sohail Khan, Zanobia Gulzar
Journal: Pure and Applied Biology (PAB)
Publisher: Bolan Society for Pure and Applied Biology
Country: Pakistan
Year: 2025
Volume: 14
Issue: 3
Language: en
Acetic acid is the second most basic carboxylic acid (following formic acid). It serves as a crucial chemical reagent and industrial chemical in multiple sectors. In homes, diluted acetic acid is frequently utilized indescaling products. In the food sector, acetic acid is regulated through food additives. Different sectors of society use and recommend vinegar as a food part, so the purpose is to evaluate vinegar consumption on brain functions and on an antioxidant defense system. The study will be helpful to understand the effects of vinegar intake as a dietary part. Current study comprises 12 rats that are divided into two groups control and test. Control was given saline while test group was given vinegar orally. Behavioral tests were performed by using apparatus including Morris water maze for memory functions, Force swimming test for depression-like symptoms while elevated plus maze used for assessing anxiety functions. Brain sample used for evaluating malondialdehyde levels. Results show that administration of vinegar significantly enhances behavioral functions as well as decreasing malondialdehyde (MDA) levels. Use of vinegar significantly affects neurobehavioral functions in rats.
Keywords: Anxiety; Depression; Memory; MDA; Vinegar
http://dx.doi.org/10.19045/bspab.2025.140073
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