DefinePK

Abstract

Ringworm, also known as dermatophytosis, is a contagious fungal disease that affects cats. The present study was conducted to observe the prevalence and therapeutic efficacy of ketoconazole, The overall prevalence of M. canis infestation was recorded as 69% in Persian cats. The age-wise prevalence was recorded higher in the younger age group (6-12 months) as compared to (1-2 years) & (3-4.5 years) cats. The gender-wise prevalence was recorded higher in females as compared to male cats at 96% and 42%, respectively. The cats confirmed that positive with M. canis were classified into four groups which were (A, B, C, and D), comprising 6 cats in each group. Group A was treated with ketoconazole, group B with Miconazole nitrate, group C with lime Sulphur and group D was kept as control and untreated. All the drugs were given topically and by the instructions from the manufacturer. The efficacy results were observed through the examination and clinical improvement of the condition. The efficacy result revealed that ketoconazole is the best drug and the cure rate was 100% as compared to lime Sulphur and Miconazole nitrate. The results were obtained at 90% and 80% respectively. Future perspectives are advancement in feline dermatology, comparative medicine, and one health approach. The benefits to the society and scientific community are improved animal welfare, advancement in veterinary medicine, development of new antifungal treatments, understanding of fungal resistance, improved diagnostic techniques, and scientific knowledge.
Keywords: Cat; DMI; ketoconazole; Lime Sulphur; M. canis; Miconazole nitrate; Pakistan;  Ringworm
http://dx.doi.org/10.19045/bspab.2025.140080