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Title: 73. Demineralized bone matrix: A cheap solution for ulna defect healing in a Pigeon
Authors: Ahmed Tunio, Jalila Abu, Dildar Hussain Kalhoro, Asmatullah Kaka, Shahid Hussain Abro, Huma Rizwana, Shazia Parveen Tunio
Journal: Pure and Applied Biology (PAB)
Publisher: Bolan Society for Pure and Applied Biology
Country: Pakistan
Year: 2021
Volume: 5
Issue: 4
Language: en
Purpose of this study was to find out whether demineralized bone matrix (DBM) could be used forulna defect healing in pigeons. For this study total 12 pigeons were purchased then divided intothree groups and placing four birds per group. Study duration was 3, 6 and 12 weeks post bonegrafting. A 1-cm bone defect was created in left ulna only then DBM graft was placed in betweenthe ulna defect and graft was covered with host tissue. Surgical wound was closed with Vicryl 3-0 suture material. Then ulna fracture was fixed with four external skeletal fixation pins (type-1).The DBM graft was prepared from donor pigeon bone using hydrochloric acid (0.6M). DBM bonegraft healing was evaluated with radiography and histology techniques. Results of radiographicassessment showed no bone graft healed after 3 and 6 weeks post-surgery, but after 12 weeks ofhealing, 50% birds showed bone union. While, histological observations showed DBM graft wassuccessfully incorporated in defect site and formed some new bone formation after 3 and 6 weeksof surgery. After 12 weeks of graft healing there was increased new bone formation and good graftincorporation. DBM graft is easy to prepare and could be useful for defect healing in birds becauseit have bone morphogenic proteins (BMP-2). This study investigated that DBM graft showedpotential effect for new bone formation and best graft for defect healing in pigeon.
Keywords: Pigeon; Allograft; Demineralized bone matrix; Bone union; Bone formation
http://dx.doi.org/10.19045/bspab.2016.50160
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