DefinePK

Abstract

The manifold cell organization permitted extraneous hydrophobic compounds to reactwith the existing compounds inside the cell. The carcinogenic and lipophilic environmental toxinsPAH provoked detrimental and noxious compounds in the interior of the cell. The cell sustainedreaction and diffusion mechanism with those lipophilic compounds. The heterogeneous cellconfiguration grew into mosaic by virtue of the membranous architectures in the vicinity of thecytoplasm. The establishment of those conglomerate cytoplasmic membranous organelles in 2Daxisymmetric geometry was absurd therefore 3D geometry was constructed. The model had beenformulated in ComsolMultiphysics by adopting the homogenization approach. The counter collation ofthe simulated results of 3D and 2D axisymmetric model were investigated. The commendable affinitydemonstrated by the results encouraged to extend the model by introducing diminutive cytoplasmicorganelles in addition with more convoluted reaction chains.